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Antibody Humanization
    Antibody Humanization

    SKU: Antibody-Humanization
    Antibody Humanization

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    Inquire for Pricing:Antibody Humanization

    Antibody Humanization

     

    Bionexus provides accurate, rapid antibody humanization by the traditional CDR grafting technique. We identify the CDRs from your antibody sequences using our own custom algorithms (a combination of traditional Kabat, IMGT and Chothia algorithms) and graft these into antibody frameworks carefully selected from a database of over 10,000 antibodies.  If required, the framework sequences are back-mutated to produce a panel of high affinity, full length, humanized antibodies for expression.

     

    Features:

                Next generation insilico CDR grafting platform

                Improvements over traditional CDR grafting methods

                T-Cell eptitope screening included in the design stage

                Chimeric control included

                3D Structural predictions included

                2-fold affinity guaranteed

                Antibodies from any species humanized

                scFvs, Fabs and other antibodies humanized

                Minimum of 10 humanized variants delivered in as little as 3-4 weeks



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